Tribenzor

Tribenzor

Generic Name: amlodipine, hydrochlorothiazide, and olmesartan (am LOE di peen, HYE droe KLOR oh THYE a zide, and OL me SAR tan)

Brand Names: Tribenzor

What is Tribenzor?

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Tribenzor contains a combination of amlodipine, hydrochlorothiazide, and olmesartan. Amlodipine is in a group of drugs called calcium channel blockers. Amlodipine relaxes (widens) blood vessels and improves blood flow.

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Olmesartan is in a group of drugs called angiotensin II receptor antagonists. Olmesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Tribenzor is used to treat high blood pressure (hypertension). This medication is usually given after others have been tried without successful treatment of hypertension.

Tribenzor may also be used for purposes not listed in this medication guide.

Important information about Tribenzor?

Do not take Tribenzor if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Do not use Tribenzor if you are allergic to amlodipine (Norvasc), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic), or olmesartan (Benicar), or if you have severe kidney disease, if you are unable to urinate, or if you are allergic to sulfa drugs.

Before you take Tribenzor, tell your doctor if you have kidney or liver disease, congestive heart failure, angina (chest pain), severe coronary artery disease, lupus, diabetes, if you are dehydrated, or if you are vomiting or having diarrhea.

You should not breast-feed while you are taking Tribenzor.

Call your doctor at once if you have any signs of an electrolyte imbalance, such as: headache, trouble concentrating, memory problems, weakness, feeling unsteady, nausea, loss of appetite, extreme thirst, increased urination, leg discomfort, jerking muscle movements, muscle weakness or limp feeling, shallow breathing, uneven heart rate, confusion, feeling tired or restless, hallucinations, fainting, or seizure.

Before taking Tribenzor

Do not use Tribenzor if you are allergic to amlodipine (Norvasc), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic), or olmesartan (Benicar), or if you have:

severe kidney disease;

if you are unable to urinate; or

if you are allergic to sulfa drugs.

To make sure you can safely take Tribenzor, tell your doctor if you have any of these other conditions:

kidney disease;

liver disease;

congestive heart failure;

angina (chest pain), severe coronary artery disease;

lupus;

diabetes;

if you are dehydrated; or

if you are vomiting or having diarrhea.

FDA pregnancy category D. Do not take Tribenzor if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking Tribenzor. It is not known whether amlodipine, hydrochlorothiazide, and olmesartan passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking Tribenzor.

See also: Tribenzor pregnancy and breastfeeding warnings (in more detail)

How should I take Tribenzor?

Take Tribenzor exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Tribenzor is usually taken once per day. Follow your doctor's instructions.

Tribenzor may be taken with or without food.

You may have new or worsening chest pain when you first start taking Tribenzor or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.

Keep using Tribenzor as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Your blood pressure will need to be checked often. Visit your doctor regularly.

Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using a thiazide diuretic.

Store Tribenzor at room temperature away from moisture and heat.

See also: Tribenzor dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme dizziness, fast or slow heartbeat, or fainting.

What should I avoid while taking Tribenzor?

Do not use potassium supplements or salt substitutes while you are taking Tribenzor, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Drinking alcohol can further lower your blood pressure and may increase certain side effects of Tribenzor.

Tribenzor side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Tribenzor: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any other serious side effects, such as:

feeling like you might pass out;

swelling in your hands, ankles, or feet;

urinating less than usual or not at all;

pain or burning when you urinate;

joint pain or swelling with fever, swollen glands, muscle aches, unusual thoughts or behavior, patchy skin color, red spots, or skin rash on your face;

headache, trouble concentrating, memory problems, weakness, feeling unsteady, hallucinations, fainting, seizure, shallow breathing;

chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; or

electrolyte imbalance-nausea, loss of appetite, uneven heart rate, extreme thirst, increased urination, leg discomfort, jerking muscle movements, muscle weakness or limp feeling, confusion, and feeling tired or restless.

Less serious Tribenzor side effects may include:

dizziness;

diarrhea;

muscle spasms;

cold symptoms such as stuffy nose, sneezing, sore throat; or

flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Tribenzor side effects (in more detail)

What other drugs will affect Tribenzor?

Tell your doctor about all other medicines you use, especially:

other medications that lower blood pressure;

heart medication or another diuretic (water pill);

potassium supplements or salt substitutes;

cholestyramine (Prevalite, Questran) or colestipol (Colestid);

insulin or oral diabetes medication;

lithium (Eskalith, LithoBid);

steroid medication such as prednisone and others;

a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton);

aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others; or

narcotic pain medication such as codeine (Tylenol #3), hydrocodone (Lortab, Vicodin, Vicoprofen), hydromorphone (Dilaudid, Palladone), oxycodone (OxyContin, Percocet), propoxyphene (Darvon, Darvocet), fentanyl (Actiq, Duragesic), methadone (Methadose, Dolophine), morphine (Kadian, MS Contin, Oramorph), and many others.

This list is not complete and other drugs may interact with Tribenzor. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Tribenzor resources

Tribenzor Side Effects (in More Detail)

Tribenzor Dosage

Tribenzor Use in Pregnancy & Breastfeeding

Tribenzor Drug Interactions

Tribenzor Support Group

2 Reviews for Tribenzor - Add your own review/rating

Tribenzor Prescribing Information (FDA)

Tribenzor Advanced Consumer (Micromedex) - Includes Dosage Information

Tribenzor MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Tribenzor with other medications

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Where can I get more information?

Your pharmacist can provide more information about Tribenzor.